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WHSC2, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89105729 Shop All Abnova Corporation Products
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89-105-729 50 μL
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Catalog No. 89-105-729 Supplier Abnova Corporation Supplier No. H00007469A01
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Mouse polyclonal antibody raised against a partial recombinant WHSC2.

This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq

Sequence: KNLSLTREQMFAAQEMFKTANKVTRPEKALILGFMAGSRENPCQEQGDVIQIKLSEHTEDLPKADGQGSTTMLVDTVFEMNYATGQWTRFKKYKPMTNV

Specifications

Antigen WHSC2
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant WHSC2.
Formulation 50% glycerol
Gene WHSC2
Gene Accession No. NM_005663
Gene Alias FLJ10442/FLJ25112/NELF-A/NELFA/P/OKcl.15
Gene Symbols WHSC2
Host Species Mouse
Immunogen WHSC2 (NP_005654, 429 a.a. ∽ 527 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7469
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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