WT1, Mouse, Clone: 6F-H2, Abnova™

Catalog No.	Quantity
89-110-907	100 μL

Catalog No. 89-110-907 Supplier Abnova Corporation Supplier No. MAB2289

Description

Mouse monoclonal antibody raised against partial recombinant WT1.

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]

Specifications

• Antigen: WT1
• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 6F-H2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant WT1.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400) Western Blot (2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris-glycine, 150mM NaCl (0.05% sodium azide)
• Gene: WT1
• Gene Alias: GUD/WAGR/WIT-2/WT33
• Gene Symbols: WT1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 1-181 of human WT1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7490
• Target Species: Human
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ