XRCC5, Mouse, Clone: 5C5, Abnova™

Catalog No.	Quantity
89-108-585	100 μL

Catalog No. 89-108-585 Supplier Abnova Corporation Supplier No. MAB10399

Description

Mouse monoclonal antibody raised against recombinant XRCC5.

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by nonhomologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq

Specifications

• Antigen: XRCC5
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 5C5
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant XRCC5.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: XRCC5
• Gene Alias: FLJ39089/KARP-1/KARP1/KU80/KUB2/Ku86/NFIV
• Gene Symbols: XRCC5
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human XRCC5.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7520
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1