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ZAP70, Mouse, PE, Clone: 1E7.2, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of ZAP70.

Manufacturer:  Abnova Corporation MAB10158

Catalog No. 89-108-407

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq

Specifications

Specifications

ZAP70
1E7.2
zeta-chain (TCR) associated protein kinase 70kDa
ZAP70
FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70
Murine
IgG1
100 Reactions
Store at 4°C. Do not freeze.
Monoclonal
Human, Murine
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
PE
In PBS (0.2% BSA, 0.09% sodium azide)
Purified
ZAP70
A synthetic peptide (conjugated with KLH) corresponding to amino acids 282-307 of human ZAP70.
Size-exclusion chromatography purification
RUO
Primary
7535
SDS
Documents
Product Certifications
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