ZAP70, Mouse, PE, Clone: 1E7.2, Abnova™

Catalog No.	Quantity
89-108-407	100 Reactions

Catalog No. 89-108-407 Supplier Abnova Corporation Supplier No. MAB10158

Description

Mouse monoclonal antibody raised against synthetic peptide of ZAP70.

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ZAP70
• Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 1E7.2
• Conjugate: PE
• Description: zeta-chain (TCR) associated protein kinase 70kDa
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: ZAP70
• Gene Alias: FLJ17670, FLJ17679, SRK, STD, TZK, ZAP-70
• Gene Symbols: ZAP70
• Host Species: Mouse
• Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 282-307 of human ZAP70.
• Purification Method: Size-exclusion chromatography purification
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7535
• Target Species: Human, Mouse
• Content And Storage: Store at 4°C. Do not freeze.
• Form: Purified
• Isotype: IgG1