Gibco™ Mouse CCL17 (TARC) Recombinant Protein, PeproTech®

Description

Recombinant Protein

Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.

Specifications

• For Use With (Application): Functional Assay
• Formulation: protein with no preservative
• Gene ID (Entrez): 20295
• Molecular Weight (g/mol): 7.9 kDa
• Name: Mouse CCL17 (TARC)
• Quantity: 100 μg
• Source: E. coli
• Regulatory Status: RUO
• Endotoxin Concentration: <1 EU/ μg
• Gene Alias: A-152E5.3; ABCD-2; CC chemokine TARC; C-C motif chemokine; C-C motif chemokine 17; C-C motif chemokine ligand 17; CCL17; chemokine (C-C motif) ligand 17; SCYA17; Scya17l; small inducible cytokine subfamily A (Cys-Cys), member 17; small inducible cytokine subfamily A17; small-inducible cytokine A17; T cell-directed CC chemokine; TARC; Thymus and activation-regulated chemokine
• Common Name: TARC
• Gene Symbol: CCL17
• Biological Activity: Determined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Sequence: ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP
• Content And Storage: -20°C
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: ≥ 98% by SDS-PAGE gel and HPLC analyses.