Invitrogen™ Mouse EphA4 Fc Chimera Recombinant Protein

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1334 μL) be added to the vial to prepare a stock solution of 0.15 mg/mL. Concentration is measured by UV.

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediated developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EphA4 encodes a protein that binds ephrin-A ligands.

Specifications

• Accession Number: Q03137
• For Use With (Application): ELISA
• Format: Lyophilized
• Formulation: PBS with 0.01% Tween 80, 5% mannitol, 5% trehalose and no preservative; pH 7.4
• Gene ID (Entrez): 13838
• Molecular Weight (g/mol): 110 kDa
• Name: Mouse EphA4 Fc Chimera
• Purification Method: SDS-PAGE
• Quantity: 200 μg
• Regulatory Status: RUO
• Endotoxin Concentration: <1.0 EU/μg
• Gene Alias: 2900005C20Rik; AI385584; Cek8; Cek8 protein; EK8; epa4; EPH receptor A4; Epha4; EPH-like kinase 8; Ephrin type-A receptor 4; Hek8; rb; receptor protein-tyrosine kinase HEK8; RGD1560587; Sek; Sek1; Tyro1; TYRO1 protein tyrosine kinase; tyrosine-protein kinase receptor MPK-3; Tyrosine-protein kinase receptor SEK; tyrosine-protein kinase receptor SEK-1; Tyrosine-protein kinase TYRO1
• Common Name: EphA4
• Gene Symbol: EPHA4
• Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA5 (at 2 μg/ml (100 μL/well) can bind mouse EFNA4-Fc with a linear range of 1.28-32 ng/mL)
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: Fc-tag
• Sequence: Mouse EPHA4, amino acids Met1-Thr547 (Accession # NP_031962.2) with a C-terminal human IgG1 Fc region
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Activity: Measured by its binding ability in a functional ELISA. Immobilized mouse EPHA5 (at 2 μg/ml (100 μL/well) can bind mouse EFNA4-Fc with a linear range of 1.28-32 ng/mL)
• Expression System: HEK293 cells
• Form: Lyophilized
• Purity or Quality Grade: >95% as determined by SDS-PAGE.