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Invitrogen™ Mouse IL-13 Recombinant Protein

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Quantity:
100 μg
25 μg
500 μg
Description
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.

Specifications
Specifications
Accession Number | P20109 |
Concentration | 200 μg/mL |
For Use With (Application) | Control, ELISA, Western Blot |
Formulation | 10 mM sodium phosphate with 150 mM NaCl and no preservative; pH 7.2 |
Gene ID (Entrez) | 16163 |
Molecular Weight (g/mol) | 11.7 kD |
Name | Mouse IL-13 (aa 26-131) |
Quantity | 25 μg |
Source | E. coli |
Storage Requirements | -20°C |
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