Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. PIRP8605

Invitrogen™ Mouse IL-2 Recombinant Protein

Catalog No. pirp8605
Click to view available options
Quantity:
20 μg

Description

Recombinant Protein

IL-2 (mouse) Recombinant Protein, RP-8605, from Invitrogen.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli. Recombinant mouse IL-4 is a non-glycosylated protein, containing 121 amino acids, with a molecular weight of 13.5 kDa. Purity is typically greater than 98% and endotoxin level less than 1 EU/ug. The expected biological activity (ED50) is determined by the dose-dependent induction of HT-2 cell proliferation and is typically less than 2ng/mL. The specific activity of this protein is 5x10^5 units/mg. Reconstitute using sterile water at 0.1mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability. Amino acid sequence: MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P04351
Concentration 0.1mg/mL
For Use With (Application) Control
Formulation 0.01M citric acid, water with no preservative; pH 4.0
Gene ID (Entrez) 16183
Name Mouse IL-2
pH Range 4.0
Quantity 20 μg
Source E. Coli
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias M-IL-2
Common Name Mouse IL-2
Gene Symbol Il2
Specific Reactivity Mouse
Conjugate Unconjugated
Cross Reactivity Ms
Species E. coli
Recombinant Recombinant
Form Lyophilized
Protein Subtype Recombinant
Purity or Quality Grade Size-exclusion - Dialysis
Show More Show Less
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.