Invitrogen™ Mouse PPAR alpha (aa 8-19) Synthetic Peptide

Description

Synthetic Peptide

Mouse PPAR alpha (residues 8-19) Synthetic Peptide, PEP-181, from Invitrogen.

Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPAR's). Nuclear hormone receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPAR's are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY-14,643, as well as by some fatty acids. It has also been shown that PPAR's can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements. PPAR, like several other nuclear hormone receptors, heterodimerizes with retinoid X receptor (RXR) alpha.

Specifications

• Gene ID (Entrez): 19013
• Species: Mouse
• Purification Method: purified
• Accession Number: P23204
• Common Name: Mouse PPAR alpha (aa 8-19)
• Concentration: 0.5 mg/mL
• Content And Storage: -20°C. Avoid freeze-thaw cycles.
• Description: Synthetic Peptide
• Format: Lyophilized
• Formulation: peptide with no preservative
• For Use With (Application): Control
• Gene Symbol: Ppara
• Lyophilized: Lyophilized
• Preservative: No preservative
• Product Type: Peptide
• Quantity: 50 μg
• Regulatory Status: RUO - research use only
• Sequence: I(8)-C-P-L-(pS)-P-L-E-A-D-D-L(19)

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov