Invitrogen eBioscience Mouse sCD40L Platinum ELISA Kit
For the quantitative detection of mouse sCD40L.
Manufacturer: Invitrogen BMS6010
DescriptionCD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T cells. The CD154 stimulates B cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD154 has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. Further, CD154 also co-stimulates proliferation of activated T cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL-2. A defect in CD154 gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. CD154 is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. CD154 is also found on some epithelial cells, carcinomas and lymphoid dendritic cells. CD154 also appears to be involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation.
|Adhesive Plate Covers|
|1 hr 20 min|
|TRAP, HIGM 1, T cell antigen Gp39, CD154|
|Colorimetric Microplate Reader|
|Serum,50 μL|Supernatant,50 μL|
|3 hr 10 min|
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