Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA5114031

Invitrogen™ MPEG1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA5114031
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA5114031 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA5114031 Supplier Invitrogen™ Supplier No. PA5114031
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: TILAVVITLA IYGTRKFKKK AYQAIEERQS LVPGTAATGD TTYQEQGQSP For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Human: 100%.

The MPEG1 (Macrophage Expressed Gene 1) gene encodes a protein known as Perforin-2, which is part of the immune system and plays a crucial role in host defense mechanisms. Located on chromosome 11, MPEG1/Perforin-2 is primarily expressed in macrophages, dendritic cells, and other immune cells. The protein functions by forming pores in the membranes of pathogenic bacteria, leading to their lysis and destruction. This pore-forming capability is integral to the innate immune response, providing a rapid means to target and eliminate intracellular pathogens. MPEG1's activity contributes significantly to the antimicrobial arsenal of the innate immune system, and deficiencies in this protein can lead to increased susceptibility to infections. Ongoing research is focused on understanding how MPEG1/Perforin-2 can be leveraged or augmented to enhance immune responses and potential therapeutic applications in infectious disease and immunotherapy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MPEG1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene Mpeg1
Gene Accession No. Q2M385
Gene Alias macrophage expressed 1; macrophage expressed gene 1; macrophage gene 1 protein; Macrophage-expressed gene 1 protein; MGC150002; MGC150003; MPEG1; MPG1; Mpg-1; MPS1; P-2; perforin 2; Perforin-2; Protein MPS1
Gene Symbols Mpeg1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human MPEG1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 219972
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.