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Tocris Bioscience™ MPEP hydrochloride Available on GSA/VA Contract for Federal Government customers only.

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

Manufacturer:  Tocris Bioscience™ 1212/50

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Catalog No. 12-125-0R


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Description

Description

Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.

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Specifications

Specifications

2-Methyl-6-(phenylethynyl)pyridine hydrochloride
>99%
Observed MW: 229.71
Soluble to 100mM in DMSO
Group I mGluR Antagonists
219911-35-0
C14H11N.HCl
50 mg
0.99
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at +4°C

SDS
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