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Description
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq]
Specifications
Specifications
| Antigen | MPO |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Monoclonal |
| Clone | 9B12G7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against human MPO. |
| Dilution | ELISA (1:10000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide). |
| Gene Symbols | MPO |
| Host Species | Mouse |
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