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Invitrogen™ MPP10 Polyclonal Antibody
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Catalog No. PIPA529465
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100 μL
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PIPA529465 100 μL
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Catalog No. PIPA529465 Supplier Invitrogen™ Supplier No. PA529465
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: MCF-7. Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (84%), Rhesus Monkey (100%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MPP10 (M-phase phosphoprotein 10), also known as MPHOSPH10, is a 681 amino acid protein that localizes to the fibrillar region of the nucleolus. Phosphorylated in the M (mitotic) phase of the cell cycle, MPP10 is a component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP) complex and is required for the early cleavages during pre-18S ribosomal RNA processing. MPP10 forms a heterotrimeric complex with IMP-3 and IMP-4, which may be required for its association with nucleolar components. The gene encoding MPP10 is localized to human chromosome 2, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MPP10
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene MPHOSPH10
Gene Accession No. O00566
Gene Alias 2810453H10Rik; 5730405D16Rik; AI326008; CT90; M phase phosphoprotein 10; M-phase phosphoprotein 10; M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Mphosph10; MPP10; MPP10P; PPP1R106; protein phosphatase 1, regulatory subunit 106; U3 small nucleolar ribonucleoprotein; U3 small nucleolar ribonucleoprotein protein MPP10
Gene Symbols MPHOSPH10
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MPHOSPH10. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10199
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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