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MPP5/PALS1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981755
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50-198-1755 100 μL
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Catalog No. 50-198-1755 Supplier Bioss Supplier No. BS11887R
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Description

Rabbit Polyclonal Antibody

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen MPP5/PALS1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MPP5
Gene Accession No. Q8N3R9
Gene Alias 3830420B02Rik; AI255216; AI644496; FLJ12615; MAGUK p55 subfamily member 5; membrane palmitoylated protein 5; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5); membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); Mpp5; palmitoylated 5; PALS1; protein associated with Lin Seven 1; Protein associated with Lin-7 1; stardust
Gene Symbols MPP5
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MPP5/PALS1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64398
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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