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Invitrogen™ MPP5 Polyclonal Antibody
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Catalog No. PIPA530966
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100 μL
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PIPA530966 100 μL
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Catalog No. PIPA530966 Supplier Invitrogen™ Supplier No. PA530966
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, U87-MG, SK-N-SH. Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (85%), Chicken (85%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MPP5 (Membrane Protein, Palmitoylated 5) plays a critical role in neurogenesis and hematopoiesis. This protein is crucial for establishing and maintaining cell polarity in epithelial cells and neurons. It is involved in the Par-3 complex, which contributes to maintaining tight junctions in epithelial cells. Mutations in MPP5 have been associated with severe neurologic impairments, including global developmental delay (GDD) and behavioral changes. In animal models, MPP5 is highly involved in the early differentiation of multipotent progenitors and supports long-term lineage-specific contributions, primarily in myeloid and lymphoid cells. MPP5 variants disrupt normal cellular function, leading to profound developmental and functional abnormalities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MPP5
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene MPP5
Gene Accession No. Q8N3R9, Q9JLB2
Gene Alias 3830420B02Rik; AI255216; AI644496; FLJ12615; MAGUK p55 subfamily member 5; membrane palmitoylated protein 5; membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 5); membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MPP5; palmitoylated 5; PALS1; protein associated with Lin Seven 1; protein associated with Lin-7 1; stardust
Gene Symbols MPP5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human MPP5. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 314259, 56217, 64398
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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