Invitrogen™ mPR gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567435

Catalog No. PIPA567435

Description

Immunogen sequence: RLFLFPGESAQ NEATSYHQK Highest antigen sequence identity to the following orthologs - mouse 80%, rat 80%.

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.

Specifications

• Antigen: mPR gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAQR5
• Gene Alias: 0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54852
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NXK6
• Gene Symbols: PAQR5
• Immunogen: Recombinant Human mPR gamma. Recombinant protein control fragment (Product #RP-108096).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov