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Invitrogen™ mPR gamma Polyclonal Antibody
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Catalog No. PIPA5106846
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100 μL
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PIPA5106846 100 μL
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Catalog No. PIPA5106846 Supplier Invitrogen™ Supplier No. PA5106846
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MPRG.

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mPR gamma
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PAQR5
Gene Accession No. Q9DCU0, Q9NXK6
Gene Alias 0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259
Gene Symbols PAQR5
Host Species Rabbit
Immunogen A synthesized peptide derived from human PAQR5(Accession Q9NXK6), corresponding to amino acid residues A296-T330.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315741, 54852, 74090
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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