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Invitrogen™ mPR gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106846

Catalog No. PIPA5106846


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Description

Description

Antibody detects endogenous levels of total MPRG.

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

mPR gamma
Polyclonal
Unconjugated
PAQR5
0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259
Rabbit
Affinity chromatography
RUO
315741, 54852, 74090
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9DCU0, Q9NXK6
PAQR5
A synthesized peptide derived from human PAQR5(Accession Q9NXK6), corresponding to amino acid residues A296-T330.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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