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Invitrogen™ mPR gamma Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5106846
Description
Antibody detects endogenous levels of total MPRG.
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
Specifications
mPR gamma | |
Polyclonal | |
Unconjugated | |
PAQR5 | |
0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259 | |
Rabbit | |
Affinity chromatography | |
RUO | |
315741, 54852, 74090 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q9DCU0, Q9NXK6 | |
PAQR5 | |
A synthesized peptide derived from human PAQR5(Accession Q9NXK6), corresponding to amino acid residues A296-T330. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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