Invitrogen™ mPR gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106846

Catalog No. PIPA5106846

Description

Antibody detects endogenous levels of total MPRG.

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.

Specifications

• Antigen: mPR gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAQR5
• Gene Alias: 0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 315741, 54852, 74090
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9DCU0, Q9NXK6
• Gene Symbols: PAQR5
• Immunogen: A synthesized peptide derived from human PAQR5(Accession Q9NXK6), corresponding to amino acid residues A296-T330.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov