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Invitrogen™ mPR gamma Polyclonal Antibody
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Catalog No. PIPA536352
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100 μL
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Catalog No. Quantity
PIPA536352 100 μL
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Catalog No. PIPA536352 Supplier Invitrogen™ Supplier No. PA536352
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 38 kDa. Purity is >95% by SDS-PAGE.

The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel, membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase and reduces intracellular cAMP, and also activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups, designated alpha, beta, and gamma, comprise this gene family. While all contain 7 transmembrane domains, they show distinct distributions in reproductive, neural, kidney and intestinal tissues. These characteristics separate them from nuclear progestin receptors, and instead imply similarity to G-protein coupled receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mPR gamma
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.2
Gene PAQR5
Gene Accession No. Q9DCU0, Q9NXK6
Gene Alias 0610010I15Rik; AV002411; BB115488; Membrane progesterone P4 receptor gamma; Membrane progesterone receptor gamma; Membrane progestin receptor gamma; mPR gamma; Mprg; PAQR5; Pmrgamma; Progesterone and adipoQ receptor family member 5; Progestin and adipoQ receptor family member 5; progestin and adipoQ receptor family member V; progestin membrane receptor gamma; RGD1311259
Gene Symbols PAQR5
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 281-330 of Human mPR gamma.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315741, 54852, 74090
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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