Invitrogen™ MPRIP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554631

Catalog No. PIPA554631

Description

Immunogen sequence: KDAYELEVLL RVKESEIQYL KQEISSLKDE LQTALRDKKY ASDKYKDIYT ELSIAKAKAD CDISRLKEQL KAATEALGEK SPDSATVSGY DIMKSKSNPD FLKKDRSCVT RQL Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Specifications

• Antigen: MPRIP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPRIP
• Gene Alias: 9530046C02; AA536749; AI647711; C76423; KIAA0864; mKIAA0864; Mprip; Mrip; M-RIP; myosin phosphatase Rho interacting protein; myosin phosphatase Rho-interacting protein; myosin phosphatase-Rho interacting protein; p116 Rho interacting protein; p116Rip; Rho interacting protein 3; rho-interacting protein 3; Rho-interacting protein 3 (p116RIP) (RIP3); RHOIP3; RIP3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116504, 23164, 26936
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P97434, Q6WCQ1, Q9ERE6
• Gene Symbols: MPRIP
• Immunogen: Recombinant protein corresponding to Human MPRIP. Recombinant protein control fragment (Product #RP-93318).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov