Invitrogen™ MPST Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528779

Catalog No. PIPA528779

Description

Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.

Specifications

• Antigen: MPST
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mpst
• Gene Alias: 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; mercaptopyruvate sulfurtransferase; MPST; MST; testicular tissue protein Li 200; tRNA thiouridin modification protein 1; TST2; TUM1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246221, 4357
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.57 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P25325, Q99J99
• Gene Symbols: Mpst
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MPST. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov