Invitrogen™ MPZL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555469

Catalog No. PIPA555469

Description

Immunogen sequence: KEIFVANGTQ GKLTCKFKST STTGGLTSVS WSFQPEGADT TVSFFHYSQG QVYLGNYPPF KDRISWAGDL DKKDASINIE NMQFIHNGTY ICDVKNPPDI VVQPGHIRLY VVEKENLPVF PVWVV Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Specifications

• Antigen: MPZL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mpzl1
• Gene Alias: 1110007A10Rik; FLJ21047; immunoglobulin family transmembrane protein; Mpzl1; MPZL1b; myelin protein zero like 1; myelin protein zero-like 1; myelin protein zero-like protein 1; protein zero related; protein zero-related; Pzr; PZR1b; PZRa; PZRb; UNQ849/PRO1787
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9019
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O95297
• Gene Symbols: Mpzl1
• Immunogen: Recombinant protein corresponding to Human MPZL1. Recombinant protein control fragment (Product #RP-91056).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG