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Invitrogen™ MPZL2 Polyclonal Antibody
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Catalog No. PIPA563891
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100 μL
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PIPA563891 100 μL
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Catalog No. PIPA563891 Supplier Invitrogen™ Supplier No. PA563891
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLFQHYRKKR WAERAHKVVE IKSKEEERLN Q Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 77%.

Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MPZL2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mpzl2
Gene Accession No. O60487
Gene Alias epithelial V-like antigen 1; EVA; Eva1; MPZL2; myelin protein zero like 2; myelin protein zero-like 2; myelin protein zero-like protein 2; UNQ606/PRO1192
Gene Symbols Mpzl2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MPZL2. Recombinant protein control fragment (Product #RP-101366).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10205
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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