Invitrogen™ MRAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA571793

Catalog No. PIPA571793

Description

MRAP2 Polyclonal Antibody for Western Blot, IHC (P)

Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Specifications

• Antigen: MRAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRAP2
• Gene Alias: bA51G5.2; BB633055; BMIQ18; C6orf117; MC2R accessory protein 2; melanocortin 2 receptor accessory protein 2; melanocortin-2 receptor accessory protein 2; Mrap2; RGD1309873
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 112609
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.87 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q96G30
• Gene Symbols: MRAP2
• Immunogen: KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human MRAP2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG