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MRAP2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981351
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100 μL
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50-198-1351 100 μL
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Catalog No. 50-198-1351 Supplier Bioss Supplier No. BS11419R
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Rabbit Polyclonal Antibody

Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP. May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Specifications

Antigen MRAP2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MRAP2
Gene Accession No. Q96G30
Gene Alias bA51G5.2; BB633055; BMIQ18; C6orf117; MC2R accessory protein 2; melanocortin 2 receptor accessory protein 2; Melanocortin-2 receptor accessory protein 2; MRAP2; RGD1309873
Gene Symbols MRAP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MRAP2 (81-130aa).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 112609
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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