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Invitrogen™ MRC2 Biosimilar Recombinant Monoclonal Antibody
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Catalog No. MA558973
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100 μg
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MA558973 100 μg
MA558974 1 mg
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Catalog No. MA558973 Supplier Invitrogen™ Supplier No. MA558973
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Description

Recombinant Monoclonal Antibody

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term Copenhagen Rigshospitalet patent anti-uPARAP.

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRC2 (Biosimilar)
Applications ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
Classification Recombinant Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
Gene MRC2
Gene Accession No. Q9UBG0
Gene Alias CD280; CLEC13E; collagen-binding factor Endo180; C-type lectin domain family 13 member E; C-type mannose receptor 2; Endo180; endocytic receptor (macrophage mannose receptor family); endocytic receptor 180; KIAA0709; Lectin lambda; macrophage mannose receptor 2; mannose receptor C type 2; mannose receptor, C type 2; mKIAA0709; Mrc2; novel lectin; UPARAP; UPAR-associated protein; urokinase-type plasminogen activator receptor-associated protein
Gene Symbols MRC2
Host Species Human
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9902
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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