Invitrogen™ MRCK alpha Polyclonal Antibody

Catalog No.	Quantity
PIPA5142110	100 μg

Catalog No. PIPA5142110 Supplier Invitrogen™ Supplier No. PA5142110

Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognise both reported Human isoforms (NP_055641.3 and NP_003598.2). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.

CDC42BPA (MRCKA) is a serine/threonine kinase which functions in actin cytoskeleton assembly and organization. Three independent coiled-coil domains and the N-terminal region preceding the kinase domain are responsible for intermolecular interactions leading to MRCK alpha multimerization. The transautophosphorylation process is critical for regulation of MRCK alpha catalytic activities. Binding of phorbol esters to MRCK releases its autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.

Specifications

• Antigen: MRCK alpha
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: CDC42BPA
• Gene Accession No.: Q5VT25
• Gene Alias: A930014J19Rik; CDC42 binding protein kinase alpha; CDC42 binding protein kinase alpha (DMPK-like); CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha; CDC42-binding protein kinase alpha (DMPK-like); CDC42BPA; cdc42bpa {ECO:0000250; DKFZp686L1738; DKFZp686P1738; DMPK-like; DMPK-like alpha; FLJ23347; Kiaa0451; MRCK; MRCK alpha; MRCKA; myotonic dystrophy kinase-related CDC42-binding kinase alpha; myotonic dystrophy kinase-related CDC-42-binding kinase-alpha; myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; myotonic dystrophy protein kinase-like alpha; mytonic dystrophy kinase-related Cdc42-binding kinase; PK428; RP5-1087E8.4; serine/threonine-protein kinase MRCK alpha; ser-thr protein kinase PK428; ser-thr protein kinase related to the myotonic dystrophy protein kinase; UniProtKB:Q5VT25}
• Gene Symbols: CDC42BPA
• Host Species: Goat
• Immunogen: Peptide with sequence SGEVRLRQLEQFI-C (aa 2-14).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8476
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG