Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA554613

Invitrogen™ MRCK beta Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA554613
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA554613 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA554613 Supplier Invitrogen™ Supplier No. PA554613
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KSKFSGAVLN VPDTSDNSKK QMLRTRSKRR FVFKVPEEER LQQRREMLRD PELRSKMISN PTNFNHVAHM GPGDGMQVLM DLPLSAVPPS QEERPGPAPT NLARQPPSRN KPYISWPSSG GSEPSVTVPL RSMSDPDQDF DKEPDSDST Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 91%.

CDC42BPB is a serine/threonine kinases which functions in actin cytoskeleton assembly and organization. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-alpha and beta (MRCK-alpha, beta) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-alpha can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-alpha can also influence neurite outgrowth promoted by Cdc42 and Rac.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRCK beta
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CDC42BPB
Gene Accession No. Q7TT49, Q7TT50, Q9Y5S2
Gene Alias CDC42 binding protein kinase beta; CDC42 binding protein kinase beta (DMPK-like); CDC42-binding protein kinase beta; CDC42-binding protein kinase beta (DMPK-like); CDC42BPB; cdc42bpb {ECO:0000312; CDC42BP-beta; DMPK-like beta; EMBL:AAP34403.1}; Kiaa1124; MRCK beta; MRCKb; myotonic dystrophy kinase related CDC42 binding kinase beta; myotonic dystrophy kinase-related CDC42-binding kinase beta; myotonic dystrophy protein kinase like beta; myotonic dystrophy protein kinase-like beta; serine/threonine-protein kinase MRCK beta
Gene Symbols CDC42BPB
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MRCK beta. Recombinant protein control fragment (Product #RP-88988).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113960, 217866, 9578
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.