Invitrogen™ MRCK gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563988

Catalog No. PIPA563988

Description

Immunogen sequence: SNDIFQVGEC RRVQQLTLSP SAGLLVVLCG RGPSVRLFAL AELENIEVAG AKIPESRGCQ VLAAGSILQA RTPVLCV Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.

CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.

Specifications

• Antigen: MRCK gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC42BPG
• Gene Alias: BC046418; CDC42 binding protein kinase gamma; CDC42 binding protein kinase gamma (DMPK-like); CDC42-binding protein kinase gamma; CDC42BPG; DMPK2; DMPK-like gamma; HSMDPKIN; KAPPA-200; MRCK gamma; MRCKG; MRCKgamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase like protein; myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; serine/threonine-protein kinase MRCK gamma
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55561
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6DT37
• Gene Symbols: CDC42BPG
• Immunogen: Recombinant protein corresponding to Human MRCK gamma. Recombinant protein control fragment (Product #RP-103424).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG