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Invitrogen™ MRG Polyclonal Antibody
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Catalog No. PIPA553534
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PIPA553534 100 μL
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Catalog No. PIPA553534 Supplier Invitrogen™ Supplier No. PA553534
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LFHAMLGHKP VGVNRHFHMI CIRDKFSQNI GRQVPSKVIW DHLSTMYDMQ ALHESEILPF PNPERNFVLP EEIIQEVREG KVMIEEEMKE EMKEDVDPHN GADDVFSSSG SLGKASEKSS KDKEKNSSDL GCKE Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.

C20orf20, also named as MRG/MORF4L-binding protein or Up-regulated in colon cancer 4 (Urcc4), is a 204 amino acid protein, which belongs to the EAF7 family. C20orf20 localizes in the nucleus and is a Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. C20orf20 is modified through phosphorylation and acetylation, so the molecular weight of C20orf20 might be 25-30 kDa.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRG
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MRGBP
Gene Accession No. Q9DAT2, Q9NV56
Gene Alias 1600027N09Rik; AW060503; C20orf20; C80444; Eaf7; FLJ10914; MRG/MORF4L binding protein; MRG/MORF4L-binding protein; MRG15BP; MRG-binding protein; MRGBP; RGD1308612; Up-regulated in colon cancer 4; Urcc4
Gene Symbols MRGBP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MRG. Recombinant protein control fragment (Product #RP-89545).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 311713, 55257, 73247
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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