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Invitrogen™ MRGD Polyclonal Antibody
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Catalog No. PIPA5100957
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100 μL
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PIPA5100957 100 μL
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Catalog No. PIPA5100957 Supplier Invitrogen™ Supplier No. PA5100957
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRGRD.

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRGD
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MRGPRD
Gene Accession No. Q8TDS7
Gene Alias Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MrgD; MRGD G protein-coupled receptor; MRGPRD; TGR7
Gene Symbols MRGPRD
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRGPRD(Accession Q8TDS7), corresponding to amino acid residues G280-A321.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116512
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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