Invitrogen™ MRGD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100957

Catalog No. PIPA5100957

Description

Antibody detects endogenous levels of total MRGRD.

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

Specifications

• Antigen: MRGD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRGPRD
• Gene Alias: Beta-alanine receptor; G protein-coupled receptor MrgD; Gm499; G-protein coupled receptor TGR7; MAS related GPR family member D; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; MAS-related gene D; MAS-related GPR, member D; mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; Mgrd; MrgD; MRGD G protein-coupled receptor; MRGPRD; TGR7
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116512
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8TDS7
• Gene Symbols: MRGPRD
• Immunogen: A synthesized peptide derived from human MRGPRD(Accession Q8TDS7), corresponding to amino acid residues G280-A321.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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