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Tocris Bioscience™ MRK 016
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Catalog No. 381710
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

α5-selective GABAA inverse agonist

GABAA receptor inverse agonist selective for the α5-subtype (EC50 = 3 nM). Exhibits affinity at benzodiazepine binding site of recombinant human GABAA receptors (Ki values are 0.77 nM, 0.83 nM, 0.85 nM and 1.4 nM for α3-, α1-, α2-, and α5-containing respectively). Increases long-term potentiation (LTP) in mouse hippocampal slices. Exhibits no anxiogenic or proconvulsant activity.

Chemical Identifiers

CAS 783331-24-8
Molecular Formula C17H20N8O2

Specifications

Quantity 10 mg
Formula Weight 368.39
Purity >98%
Molecular Weight (g/mol) 368.401
Chemical Name or Material MRK 016

Safety and Handling

Recommended Storage Store at +4°C
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