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MRK 016, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
GABAA receptor inverse agonist selective for the α5-subtype (EC50 = 3 nM). Exhibits affinity at benzodiazepine binding site of recombinant human GABAA receptors (Ki values are 0.77 nM, 0.83 nM, 0.85 nM and 1.4 nM for α3-, α1-, α2-, and α5-containing respectively). Increases long-term potentiation (LTP) in mouse hippocampal slices. Exhibits no anxiogenic or proconvulsant activity.
Specifications
Quantity | 10 mg |
Formula Weight | 368.39 |
Percent Purity | >98% |
Chemical Name or Material | MRK 016 |
Safety and Handling
Recommended Storage | Store at +4°C |
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