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MRP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501567672
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50-156-7672 100 μL
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Catalog No. 50-156-7672 Supplier Bethyl Laboratories, Inc Supplier No. A304419A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.

Specifications

Antigen MRP1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene ABCC1
Gene Accession No. P33527
Gene Alias Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Leukotriene C(4) transporter; LTC4 transporter; MRP1; MRP; ABCC1
Gene Symbols ABCC1
Host Species Rabbit
Immunogen Between 275 and 325
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4363
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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