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Invitrogen™ MRP7 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA559646
Description
Immunogen sequence: RLEEYTCDLP QEPQGQPLQL GTGWLTQGGV EFQDVVLAYR PGLPNALDGV TFCVQPGEKL GIVG Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 78%.
The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.
Specifications
MRP7 | |
Polyclonal | |
Unconjugated | |
ABCC10 | |
ABCC10; ATP binding cassette subfamily C member 10; ATP-binding cassette sub-family C member 10; ATP-binding cassette, subfamily C (CFTR/MRP), member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; EST182763; mFLJ00002; Mrp7; Multidrug resistance-associated protein 7; SIMRP7 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
89845 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q5T3U5 | |
ABCC10 | |
Recombinant protein corresponding to Human MRP7. Recombinant protein control fragment (Product #RP-94746). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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