Invitrogen™ MRP2 Recombinant Rabbit Monoclonal Antibody (6L3Z6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542921

Catalog No. PIMA542921

Description

Positive test controls include: HepG2, A-549. Immunogen sequence: CLGRALLRKS KILVLDEATA AVDLETDNLI QTTIQNEFAH CTVITIAHRL HTIMDSDKVM VLDNGKIIEC GSPEELLQIP GPFYFMAKEA GIENVNSTKF.

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRP2
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q92887
• Gene Symbols: ABCC2
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1446-1545 of human MRP2/ABCC2 (Q92887).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 6L3Z6
• Conjugate: Unconjugated
• Gene: ABCC2
• Gene Alias: ABC30; Abcc2; AI173996; ATP binding cassette subfamily C member 2; ATP-binding cassette sub-family C member 2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; calicular multispecific organic anion transporter; canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Cmoat; CMOAT1; Cmrp; DJS; Human MRP2; KIAA1010; MRP2; multidrug resistance associated protein 2; multidrug resistance protein 2; multidrug resistance-associated protein 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1244
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid