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Invitrogen™ MRP3 Monoclonal Antibody (M3II-9)
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Catalog No. 01671086
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Catalog No. Quantity
01-671-086 1 mL
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Catalog No. 01-671-086 Supplier Invitrogen™ Supplier No. MA135680
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Description

Mouse Monoclonal Antibody

M3II-9 reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-9 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-9 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
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Specifications

Antigen MRP3
Applications Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone M3II-9
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
Gene ABCC3
Gene Accession No. O15438
Gene Alias ABC31; ABCC3; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; cMOAT2; DKFZp686E22157; EST90757; MLP2; MLP-2; MOAT-D; Mrp3; MRP-like protein 2; multidrug resistance associated protein; multidrug resistance protein 3; multidrug resistance-associated protein 3; multi-specific organic anion transporter D; organic anion transporter
Gene Symbols ABCC3
Host Species Mouse
Immunogen MRP3 aa 830-949.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8714
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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