Invitrogen™ MRP4 Monoclonal Antibody (M4I-10)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA135681

Catalog No. 01-671-087

Description

MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-10 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Specifications

• Antigen: MRP4
• Classification: Monoclonal
• Concentration: 100 μg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: O15439
• Gene Symbols: ABCC4
• Immunogen: Maltose Binding Protein and aa 372-431 of MRP4.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Clone: M4I-10
• Conjugate: Unconjugated
• Gene: ABCC4
• Gene Alias: ABCC4; ABC-tranporter; ATP binding cassette subfamily C member 4; ATP-binding cassette protein C4; ATP-binding cassette sub-family C member 4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); D630049P08Rik; EST170205; MOATB; MOAT-B; MRP/cMOAT-related ABC transporter; MRP4; Multidrug resistance-associated protein 4; multi-specific organic anion transporter B; RP11-74A12.1
• Host Species: Rat
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10257, 239273
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

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