Invitrogen™ MRP4 Monoclonal Antibody (M4I-80)

Rat Monoclonal Antibody

Supplier:  Invitrogen™ MA135682

Catalog No. 01-671-088

Description

The M4I-80 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431. MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-80 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Specifications

• Antigen: MRP4
• Classification: Monoclonal
• Concentration: 200 μg/mL
• Formulation: tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
• Gene Accession No.: O15439
• Gene Symbols: ABCC4
• Immunogen: MRP4 aa 372-431.
• Regulatory Status: RUO
• Gene ID (Entrez): 10257, 239273
• Content And Storage: 4°C
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Clone: M4I-80
• Conjugate: Unconjugated
• Gene: ABCC4
• Gene Alias: ABCC4; ABC-tranporter; ATP binding cassette subfamily C member 4; ATP-binding cassette protein C4; ATP-binding cassette sub-family C member 4; ATP-binding cassette, subfamily C (CFTR/MRP), member 4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); D630049P08Rik; EST170205; MOATB; MOAT-B; MRP/cMOAT-related ABC transporter; MRP4; Multidrug resistance-associated protein 4; multi-specific organic anion transporter B; RP11-74A12.1
• Host Species: Rat
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG2a

Safety and Handling

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