Invitrogen™ MRPL11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106570

Catalog No. PIPA5106570

Description

Antibody detects endogenous levels of total MRPL11.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.

Specifications

• Antigen: MRPL11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL11
• Gene Alias: 2410001P07Rik; 39S ribosomal protein L11, mitochondrial; CGI-113; cgi-113 protein; L11mt; mgc111024; Mitochondrial large ribosomal subunit protein uL11m; mitochondrial ribosomal protein L11; Mrpl11; MRP-L11
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293666, 65003, 66419
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5XIE3, Q9CQF0, Q9Y3B7
• Gene Symbols: MRPL11
• Immunogen: A synthesized peptide derived from human MRPL11(Accession Q9Y3B7), corresponding to amino acid residues P31-K81.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov