Invitrogen™ MRPL11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596308

Catalog No. PIPA596308

Description

Immunogen sequence: MSKLGRAARG LRKPEVGGVI RAIVRAGLAM PGPPLGPVLG QRGVSINQFC KEFNERTKDI KEGIPLPTKI LVKPDRTFEI KIGQPTVSYF LKAAAGIEKG ARQTGKEVAG LVTLKHVYEI ARIKAQDEAF ALQDVPLSSV VRSIIGSARS LGIRVVKDLS SEELAAFQKE RAIFLAAQKE ADLAAQEEAA KK; Positive Samples: HepG2, HeLa, MCF7, A-549, Mouse kidney, Mouse brain, Mouse heart, Rat heart; Cellular Location: Mitochondrion.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.

Specifications

• Antigen: MRPL11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL11
• Gene Alias: 2410001P07Rik; 39S ribosomal protein L11, mitochondrial; CGI-113; cgi-113 protein; L11mt; mgc111024; Mitochondrial large ribosomal subunit protein uL11m; mitochondrial ribosomal protein L11; Mrpl11; MRP-L11
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 293666, 65003, 66419
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q5XIE3, Q9CQF0, Q9Y3B7
• Gene Symbols: MRPL11
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human MRPL11 (NP_0571341).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG