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Invitrogen™ MRPL12 Polyclonal Antibody
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Catalog No. PIPA530159
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100 μL
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PIPA530159 100 μL
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Catalog No. PIPA530159 Supplier Invitrogen™ Supplier No. PA530159
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, H1299, HeLa, HepG2, mouse brain. Predicted reactivity: Mouse (84%), Rat (82%), Rhesus Monkey (94%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion. MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs. Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation. MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit. MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL12
Applications Immunohistochemistry (Paraffin), Western Blot, Proximity Ligation Assay, Immunocytochemistry
Classification Polyclonal
Concentration 0.56 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene MRPL12
Gene Accession No. P52815, Q9DB15
Gene Alias 0610034O11Rik; 1500031N16Rik; 39S ribosomal protein L12, mitochondrial; 5c5-2; FLJ60124; hypothetical protein LOC550391; im:6893415; L12mt; MGC8610; Mitochondrial large ribosomal subunit protein bL12m; mitochondrial ribosomal protein L12; mitochondrial ribosomal protein L7/12; MRPL12; MRP-L12; MRP-L31/34; MRPL7; MRPL7/L12; ribosomal protein, mitochondrial, L12; Rpm12; RPML12; zgc:112445
Gene Symbols MRPL12
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MRPL12. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56282, 6182
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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