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MRPL12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 147951AP150UL

Encompass_Preferred

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Catalog No. 50-172-9726


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Description

Description

The antibody reacts specifically with 21 kDa MRPL12 protein.

MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion. MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs. Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation. MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit. MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.
Specifications

Specifications

MRPL12
Polyclonal
Unconjugated
MRPL12
5c5 2, L12mt, MRP L12, MRP L31/34, MRPL12, MRPL7, MRPL7/L12, RPML12
Rabbit
Antigen Affinity Chromatography
RUO
303746, 56282, 6182
-20°C
Liquid
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P52815, Q9DB15
Mrpl12
MRPL12 Fusion Protein Ag6504
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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