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Invitrogen™ MRPL18 Polyclonal Antibody
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Catalog No. PIPA5101355
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PIPA5101355 100 μL
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Catalog No. PIPA5101355 Supplier Invitrogen™ Supplier No. PA5101355
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL18.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL18
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Mrpl18
Gene Accession No. Q9CQL5, Q9H0U6
Gene Alias 1010001C05Rik; 39S ribosomal protein L18, mitochondrial; C79879; HSPC071; L18mt; Mitochondrial large ribosomal subunit protein uL18m; mitochondrial ribosomal protein L18; Mrpl18; MRP-L18
Gene Symbols Mrpl18
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPL18(Accession Q9H0U6), corresponding to amino acid residues L24-S74.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29074, 67681
Target Species Human, Mouse, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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