Invitrogen™ MRPL18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531875

Catalog No. PIPA531875

Description

Recommended positive controls: NT2D1, PC-3, U87-MG. Predicted reactivity: Mouse (86%), Rat (84%), Rhesus Monkey (97%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.

Specifications

• Antigen: MRPL18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mrpl18
• Gene Alias: 1010001C05Rik; 39S ribosomal protein L18, mitochondrial; C79879; HSPC071; L18mt; Mitochondrial large ribosomal subunit protein uL18m; mitochondrial ribosomal protein L18; Mrpl18; MRP-L18
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29074
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.8 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9H0U6
• Gene Symbols: Mrpl18
• Immunogen: Recombinant protein fragment corresponding to a region within amino acids 1 and 208 of Human MRPL18.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG