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Invitrogen™ MRPL18 Polyclonal Antibody
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Catalog No. PIPA531875
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100 μL
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PIPA531875 100 μL
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Catalog No. PIPA531875 Supplier Invitrogen™ Supplier No. PA531875
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, PC-3, U87-MG. Predicted reactivity: Mouse (86%), Rat (84%), Rhesus Monkey (97%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L18P ribosomal protein family. Three polymorphic sites exist in this gene, one of which is three nt in length which causes an extra aa near the N-terminus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL18
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.8 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Mrpl18
Gene Accession No. Q9H0U6
Gene Alias 1010001C05Rik; 39S ribosomal protein L18, mitochondrial; C79879; HSPC071; L18mt; Mitochondrial large ribosomal subunit protein uL18m; mitochondrial ribosomal protein L18; Mrpl18; MRP-L18
Gene Symbols Mrpl18
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MRPL18. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29074
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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