Invitrogen™ MRPL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552436

Catalog No. PIPA552436

Description

Immunogen sequence: PAPSLFPAAQ MMNNGLLQQP SALMLLPCRP VLTSVALNAN FVSWKSRTKY TITPVKMRKS GGRDHTGRIR VHGIGGGHKQ RYRMIDFLRF RPEETKSGPF EEKVIQVRYD P Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014].

Specifications

• Antigen: MRPL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL2
• Gene Alias: 39S ribosomal protein L2, mitochondrial; CGI-22; L2mt; Mitochondrial large ribosomal subunit protein uL2m; mitochondrial ribosomal protein L2; MRP-L14; MRPL2; MRP-L2; ribosomal protein, mitochondrial, L14; Rpml14
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51069
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5T653
• Gene Symbols: MRPL2
• Immunogen: Recombinant protein corresponding to Human MRPL2. Recombinant protein control fragment (Product #RP-90112).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG