Invitrogen™ MRPL21 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101357

Catalog No. PIPA5101357

Description

Antibody detects endogenous levels of total MRPL21.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).

Specifications

• Antigen: MRPL21
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL21
• Gene Alias: 39S ribosomal protein L21, mitochondrial; BC028768; D9Wsu149; L21mt; Mitochondrial large ribosomal subunit protein bL21m; mitochondrial ribosomal protein L21; Mrpl21; MRP-L21; Unknown (protein for MGC:133585)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 219927, 309140, 353242
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q7Z2W9, Q9D1N9
• Gene Symbols: MRPL21
• Immunogen: A synthesized peptide derived from human MRPL21(Accession Q7Z2W9), corresponding to amino acid residues R23-T73.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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