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Invitrogen™ MRPL22 Polyclonal Antibody
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Catalog No. PIPA5101358
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100 μL
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PIPA5101358 100 μL
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Catalog No. PIPA5101358 Supplier Invitrogen™ Supplier No. PA5101358
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL22.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL22
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MRPL22
Gene Accession No. P0C2C0, Q8BU88, Q9NWU5
Gene Alias 39S ribosomal protein L22, mitochondrial; 39S ribosomal protein L25, mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; Mitochondrial large ribosomal subunit protein uL22m; mitochondrial ribosomal protein L22; Mrpl22; MRP-L22; MRPL25; MRP-L25; RPML25
Gene Symbols MRPL22
Host Species Rabbit
Immunogen A synthesized peptide derived from human MRPL22(Accession Q9NWU5), corresponding to amino acid residues A96-C146.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 216767, 287302, 29093
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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