Invitrogen™ MRPL22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101358

Catalog No. PIPA5101358

Description

Antibody detects endogenous levels of total MRPL22.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRPL22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL22
• Gene Alias: 39S ribosomal protein L22, mitochondrial; 39S ribosomal protein L25, mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; Mitochondrial large ribosomal subunit protein uL22m; mitochondrial ribosomal protein L22; Mrpl22; MRP-L22; MRPL25; MRP-L25; RPML25
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 216767, 287302, 29093
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P0C2C0, Q8BU88, Q9NWU5
• Gene Symbols: MRPL22
• Immunogen: A synthesized peptide derived from human MRPL22(Accession Q9NWU5), corresponding to amino acid residues A96-C146.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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