Invitrogen™ MRPL22 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561416

Catalog No. PIPA561416

Description

Immunogen sequence: IKEVLLQAQD MAVRDHNVEF RSNLYIAEST SGRGQCLKRI RYHGRGRFGI MEKVYCHYFV KLVEGPPPPP EPPKTAVAHA KEYIQQLRSR TIVHTL Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRPL22
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL22
• Gene Alias: 39S ribosomal protein L22, mitochondrial; 39S ribosomal protein L25, mitochondrial; E030011D16Rik; HSPC158; L22mt; L25mt; Mitochondrial large ribosomal subunit protein uL22m; mitochondrial ribosomal protein L22; Mrpl22; MRP-L22; MRPL25; MRP-L25; RPML25
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29093
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NWU5
• Gene Symbols: MRPL22
• Immunogen: Recombinant protein corresponding to Human MRPL22. Recombinant protein control fragment (Product #RP-100662).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov